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Global Sepsis Challenge

We can help save 1.3 million lives per year through effective sepsis awareness, treatment and prevention.

Sepsis - A Global Health Priority

Sepsis is a life-threatening condition that arises when the body’s response to an infection injures its own tissues and organs.

With an estimated 30 million episodes of sepsis globally each year and 9 million deaths, sepsis cases are growing by circa 10% per year. Sepsis mortality is higher than breast, bowel and prostrate cancer combined.

Sepsis is now the second largest cause of mortality in the UK; and accounts for the highest area of medical spend in the US, costing $20bn/year.

In May 2017, the World Health Organization and the World Health Assembly categorised sepsis as a global health priority.

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In response, escalla are combining the latest medical information, expert planning and implementation strategies to offer tailored solutions to raise awareness, improve treatment and reduce mortality associated with sepsis.  We work closely with the Global Sepsis Alliance and the UK Sepsis Trust.

With our passion and commitment, alongside a proven track record of combining subject matter experts, change management and effective learning programmes, we aim to reduce the human and financial cost associated with this widespread condition.

Our sepsis work supports our goal of generating localised, sustainable improvement within the global health sector.

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Our work with the Ministry of Health
Kingdom of Saudi Arabia (KSA)

We have carried out two studies, commissioned by the KSA Ministry of Health, focusing on sepsis treatment, compliance and outcomes for a seven-hospital cluster.

Sepsis in Saudi Arabia is recognised as being a key contributor to an estimated 64,000 deaths every year. To address this, we put together an improvement programme, outlining new systems and processes for sepsis treatment and recognition, which has the potential to save 32,000 lives every year. This would result in a 25% reduction in sepsis-related deaths in young adults. It would also have the added benefit of improving annual productivity by an estimated £1,709,000,000.

The Challenge

To educate health professionals across the Kingdom of Saudi Arabia to diagnose and treat sepsis – reducing the number of sepsis related deaths.

The Solution

  • Examined how global best-practice could be regionalised.
  • Recommended early warning systems and treatment bundles.
  • Designed and delivered a blended learning programme, using face to face training, e-learning and online compliance.

The Outcome

The sepsis improvement programme is forecasted to deliver:

  • 32,000 lives saved per year.
  • £1.7bn boost to annual productivity.
  • £320m savings annually (reduced hospital admissions).
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Our work helped the Kingdom of Saudi Arabia to win an award from the Global Sepsis Alliance, for improving the diagnosis and clinical management of sepsis. This involved delivering a learning platform and national learning programme to healthcare professionals, teaching about the dangers of sepsis and how to effectively deal with the condition at all stages.


Our mission is to save lives, and to reduce the economic burden arising from sepsis-related illnesses.

We can achieve this by creating consistent, repeatable change within hospital facilities and management – offering new approaches that are highly effective and can be replicated across different healthcare environments.

Using integrated subject matter experts, the latest medical information, and proven tools and processes, we can overcome the sepsis challenge to create sustainable environments where front-line staff are effectively trained and empowered to make positive change.

In partnering with escalla, we can support your journey of saving lives. We can help you in three areas:

Initial Consultancy

  • Set the agenda
  • Define the “opportunity”
  • Create the business case
  • Engage stakeholders

Data Collection/

  • Understanding “Current State”
  • Examining leading Sepsis models
  • Regionalising to local health economy
  • Recommendations for specific tools
    • Early recognition tools
    • Effective Treatment Bundles

Change Programme

Create an effective change programme

  • Ownership & Leadership
  • Changing Behaviours
  • Standardised Methods
  • Reinforcement & Reliability
  • Save Lives

Act now – at a national level for each weeks’ delay in deploying the change programme in Saudi Arabia, 615 lives were lost, with an associated £33m productivity loss. The hospital spend in dealing with the 615 sepsis cases would equate to circa £6m – all of these could have been avoided with early recognition tools and effective treatment bundles.

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